0

‘Unusual’ form of cell death underlies lung damage in Covid patients, finds study – ET HealthWorld

New Delhi: A unique look cell death can lead to a lungs of covid patient Excessive damage is occurring, resulting in potentially life-threatening conditions Swelling And acute respiratory disordersas per new Research, Ability to prevent this abnormal form of cell death – ferroptosis – COVID-19 could offer doctors new ways to treat lungs DiseaseThe study suggested.

Cell death, in which the cell stops functioning, can be natural or triggered by causes such as disease or injury.

The most common form of cell death is cells “cutting off” the molecules inside, the researchers said, adding that it also happens in humans when they become sick or age.

However, in ferroptosis, a relatively uncommon form of cell death, cells die because their outer fat layers collapse, the researchers found. Columbia UniversityUS, said.

In this study, they analyzed human tissues and collected autopsies patients who died respiratory failure Samples from hamsters infected with COVID-19 infection were also analyzed.

The team found that most of the cells were dying through the mechanism of ferroptosis, underlying the lung disease. covid patient,

Therefore, drugs that target and prevent the ferroptosis form of cell death may help improve it Treatment course for COVID-19, the researchers said.

“This discovery adds important insights to our understanding of how COVID-19 affects the body, helping us fight life-threatening cases of the disease,” said Brent Stockwell, MD, chair and co-chair of the department of biological sciences at Columbia. Our capability will be greatly improved.” -Lead author of the study published in the journal nature communication,

Previous studies have shown that ferroptosis is certainly important normal body processesCan also attack and kill healthy cells in patients neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease,

The authors said the ability to inhibit ferroptosis could provide doctors with new ways to fight cell death This should not happen, as is the case with COVID-19 lung disease.

“We hope that these important new findings can improve our ability to combat this Deadly disease”In many cases, this leads to negative health effects and even death,” Stockwell said.

  • Published May 21, 2024 at 10:39am IST

Join a community of 2M+ industry professionals

Subscribe to our newsletter to receive the latest information and analysis.

Download ETHealthworld App

  • Get realtime updates
  • Save your favorite articles

icon g play - 2

icon app store - 4


scan to download app
health barcode - 6

unusual-form-of-cell-death-underlies-lung-damage-in-covid-patients-finds-study-et-healthworld